Most Recent Publications
Inter-center variation in autopsy practices among regional neonatal intensive care units (NICUs).
https://www.nature.com/articles/s41372-021-01286-1
https://pubmed.ncbi.nlm.nih.gov/34711937/
Association of Time of First corticosteroid Treatment with BPD in Preterm Infants. https://pubmed.ncbi.nlm.nih.gov/34379886/
A Comparison of newer Classifications of BPD: Findings from the CHNC Severe BPD Group: https://pubmed.ncbi.nlm.nih.gov/34354227/
Qualitative indication for Tracheostomy and Chronic Mechanical Ventilation in Patient with severe BPD: https://pubmed.ncbi.nlm.nih.gov/34349231/
Survey of Quaternary Neonatal Management of Post-Hemorrhagic Hydrocephalus: https://pubmed.ncbi.nlm.nih.gov/34293803/
Integrated Cardiac Care Models of Neonates with Congenital Heart Disease: the Evolving Role of the Neonatologist: https://pubmed.ncbi.nlm.nih.gov/34140645/
Medical and Surgical Interventions and Outcomes for Infants with Trisomy 18 (T18) or Trisomy 13 (T13) at Children’s Hospitals Neonatal Intensive Care Units (NICUs): https://pubmed.ncbi.nlm.nih.gov/34112961/
Analgesia, Sedation, and Neuromuscular Blockade in Infants with CDH: https://pubmed.ncbi.nlm.nih.gov/34044457/
Venovenous vs. Venoarterial extracorporeal membrane oxygenation among infants with HIE: is there a difference in outcome? https://pubmed.ncbi.nlm.nih.gov/34012056/
Withdrawal of Artificial Nutrition and Hydration: a survey of level IV neonatal intensive care units: https://pubmed.ncbi.nlm.nih.gov/33758396/
Treatment of Pulmonary Hypertension during Initial Hospitalization in a multicenter cohort of infants with CDH: https://pubmed.ncbi.nlm.nih.gov/33649432/
Central Line Utilization and Complications in Infants with Congenital Diaphragmatic Hernia: https://pubmed.ncbi.nlm.nih.gov/33535242/
Premature Congenital Heart Disease: Building a Comprehensive Database to Evaluate Risks & Guide Intervention https://pubmed.ncbi.nlm.nih.gov/33253730/
Non-Invasive Neuro-Critical Care Monitoring for Neonates on Extracorporeal Membrane Oxygenation: were do we stand?: https://pubmed.ncbi.nlm.nih.gov/32753710/
Home Oxygen Use and 1-Year Readmission among infants born Preterm with BPD Discharged from Children’s Hospitals Neonatal Intensive Care Units: https://pubmed.ncbi.nlm.nih.gov/32093927/
Center, Gestational Age, and Race Impact End of Life Care Practices at Regional Neonatal Intensive Care Units: https://pubmed.ncbi.nlm.nih.gov/31831163/
Implications of Continuity of care on Infant Caloric Intake in the Neonatal Intensive Care Unit: https://pubmed.ncbi.nlm.nih.gov/32157220/
Low Prevalence of clinical decision support to calcualte caloric and Fluid intake for infants in the NICU: https://pubmed.ncbi.nlm.nih.gov/31813935/
Machine Learning Mortality Classification in the Clinical Documentation with Increase Accuracy in Visual-Based Anlayses: https://pubmed.ncbi.nlm.nih.gov/31762098/
Antimicrobial Therapy Utilization in Neonates with HIE: https://pubmed.ncbi.nlm.nih.gov/31611619/
Utiliity of Echocardiography in predicting Mortality in infants with Severe BPD: https://pubmed.ncbi.nlm.nih.gov/31570799/
Extracorporeal Membrane Oxygenation and Bloodstream Infection in CDH: https://pubmed.ncbi.nlm.nih.gov/31383944/
Inter-center variation in autopsy practices among regional neonatal intensive care units (NICUs)
Objective: To characterize infants who underwent autopsy in regional neonatal intensive care units (NICUs) and examine inter-center variability in autopsy completion Study design: Retrospective cohort study of infants who died between 2010 and 2016 from 32 participating hospitals in the
Predicting Treatment of Pulmonary Hypertension at Discharge in Infants with CDH
Objective: To predict pulmonary hypertension (PH) therapy at discharge in a large multicenter cohort of infants with congenital diaphragmatic hernia (CDH) Study design: Six-year linked records from Children’s Hospitals Neonatal Database and Pediatric Health Information System were …
Association of Neonatologist Continuity of Care and Short-Term Patient Outcomes
Machut KZ, Datta A, Stoller JZ, Rao R, Mathur A, Grover TR, Billimoria Z, Murthy K J Pediatr 2019 Jun 11 pii: S0022-3476(19)30589-X doi: 101016/jjpeds201905023 PMID: 31201026 Objectives To describe neonatologist continuity of care and estimate
Does the initial surgery for necrotizing enterocolitis matter? Comparative outcomes for laparotomy vs. peritoneal drain as initial surgery for necrotizing enterocolitis in infants <1000 g birth weight
Yanowitz TD, Sullivan KM, Piazza AJ, Brozanski B, Zaniletti I, Sharma J, DiGeronimo R, Nayak SP, Wadhawan R, Reber KM, Murthy K; CHND Surgical NEC Focus Group J Pediatr Surg 2019 Apr;54(4):712-717 doi: 101016/jjpedsurg201812010 Epub 2019 Jan 19PMID: 30765157 Purpose Quantify
Transforming Care for Medically Complex Infants: Accomplishments & Future Directions of the CHNC and CHND
The Children’s Hospitals Neonatal Consortium is a quality outcome organization for neonatology leaders based in Level IV neonatal intensive care units (NICUs) The CHNC formed in 2006 and partnered with the Child Health Corporation of America (now Children’s Hospital Association (CHA)) to …
Improving Care for Medically Complex Infants: Accomplishments and Future Direction of the CHNC Collaborative Initiatives for Quality Improvement
The Children’s Hospitals Neonatal Consortium (CHNC) established the CHNC Collaborative Initiatives for Quality Improvement (CIQI) in 2009 The CHNC CIQI was developed for participating hospitals in the Children’s Hospitals Neonatal Database (CHND) to provide structure for quality improvement …
Inter-center variation in death or tracheostomy placement in infants with severe bronchopulmonary dysplasia
Objective: To estimate the presence and sources of inter-center variation (ICV) in the risk of death or tracheostomy placement (D/T) among infants with severe bronchopulmonary dysplasia (sBPD) Study design: We analyzed the Children’s Hospitals Neonatal Database between 2010 and 2013
Short-term weight gain velocity in infants with congenital diaphragmatic hernia (CDH)
Background: Appropriate post-natal growth remains a mainstay of therapeutic goals for infants with CDH, with the hypothesis that optimizing linear growth will improve survival through functional improvements in pulmonary hypoplasia However, descriptions of growth and the effect on survival are
Nutritional Practices and Growth in Premature Infants After Surgical Necrotizing Enterocolitis
OBJECTIVE: The aim of the study was to describe the nutritional provisions received by infants with surgical necrotizing enterocolitis (NEC) and the associated effects on short-term growth METHODS: Through the Children’s Hospitals Neonatal Database, we identified infants born ≤32 …
Intercenter Cost Variation for Perinatal Hypoxic-Ischemic Encephalopathy in the Era of Therapeutic Hypothermia
Objective: To quantify intercenter cost variation for perinatal hypoxic ischemic encephalopathy (HIE) treated with therapeutic hypothermia across children’s hospitals Study design: Prospectively collected data from the Children’s Hospitals Neonatal Database and Pediatric Health …
Predicting death or extended length of stay in infants with congenital diaphragmatic hernia
Objective: To predict mortality or length of stay (LOS) >109 days (90th percentile) among infants with congenital diaphragmatic hernia (CDH) Study Design: We conducted a retrospective analysis using the Children’s Hospital Neonatal Database during 2010 to 2014 Infants born >34
SLUG Bug: Quality Improvement With Orchestrated Testing Leads to NICU CLABSI Reduction
Objective: Reduce central line–associated bloodstream infection (CLABSI) rates 15% over 12 months in children’s hospital NICUs Use orchestrated testing as an approach to identify important CLABSI prevention practices Methods: Literature review, expert opinion, and benchmarking were used to …
Orchestrated Testing: An Innovative Approach to a Multicenter Improvement Collaborative
Health care quality improvement collaboratives implement care bundles to target critical parts of a complex system to improve a specific health outcome The quantitative impact of each component of the care bundle is often unknown Orchestrated testing (OT) is an
Interdisciplinary Teamwork and the Power of a Quality Improvement Collaborative in Tertiary Neonatal Intensive Care Units
Significant gaps in healthcare quality and outcomes can be reduced via quality improvement collaboratives (QICs), which improve care by leveraging data and experience from multiple organizations The Children’s Hospital Neonatal Consortium Collaborative Initiatives for Quality Improvement team …
Short-term outcomes after perinatal hypoxic ischemic encephalopathy: a report from the Children’s Hospitals Neonatal Consortium HIE focus group
Objective: To characterize infants affected with perinatal hypoxic ischemic encephalopathy (HIE) who were referred to regional neonatal intensive care units (NICUs) and their related short-term outcomes Study Design: This is a descriptive study evaluating the data collected prospectively in the
Short-Term Outcomes and Medical and Surgical Interventions in Infants with Congenital Diaphragmatic Hernia
Objective: The aim of this study is to characterize medical and surgical therapies and short-term outcomes in infants with congenital diaphragmatic hernia (CDH) Study Design: Retrospective analysis of CDH infants admitted to 27 children’s hospitals submitting data to Children’s …
Short-term outcomes for preterm infants with surgical necrotizing enterocolitis
Objective: To characterize the population and short-term outcomes in preterm infants with surgical necrotizing enterocolitis (NEC) Study Design: Preterm infants with surgical NEC were identified from 27 hospitals over 3 years using the Children’s Hospitals Neonatal Database; infants with …
High surgical burden for infants with severe chronic lung disease (sCLD)
Background/purpose: Infants with severe chronic lung disease (sCLD) may require surgical procedures to manage their medical problems; however, the scope of these interventions is undefined The purpose of this study was to characterize the frequency, type, and timing of operative
The Children’s Hospitals Neonatal Database: an overview of patient complexity, outcomes and variation in care
The Children’s Hospitals Neonatal Consortium is a multicenter collaboration of leaders from 27 regional neonatal intensive care units (NICUs) who partnered with the Children’s Hospital Association to develop the Children’s Hospitals Neonatal Database (CHND), launched in 2010 The …
Predicting death or tracheostomy placement in infants with severe bronchopulmonary dysplasia
Objective: To estimate the risk of death or tracheostomy placement (D/T) in infants with severe bronchopulmonary dysplasia (sBPD) born <32 weeks’ gestation referred to regional neonatal intensive care units Study Design: We conducted a retrospective cohort study in infants born
The association of type of surgical closure on length of stay among infants with gastroschisis born ≥ 34 weeks’ gestation
Background/Purpose: The optimal surgical approach in infants with gastroschisis (GS) is unknown The purpose of this study was to estimate the association between staged closure and length of stay (LOS) in infants with GS Design/Methods: We used the Children’s Hospital
Postnatal Weight Gain in Preterm Infants with Severe Bronchopulmonary Dysplasia
Objectives: To characterize postnatal growth failure (PGF), defined as weight < 10th percentile for postmenstrual age (PMA) in preterm (≤ 27 weeks’ gestation) infants with severe bronchopulmonary dysplasia (sBPD) at specified time points during hospitalization, and to compare these …
Therapeutic interventions and short-term outcomes for infants with severe bronchopulmonary dysplasia born at <32 weeks’ gestation
Objective: To characterize the treatments and short-term outcomes in infants with severe bronchopulmonary dysplasia (sBPD) referred to regional neonatal intensive care units Study Design: Infants born <32 weeks’ gestation with sBPD were identified using the Children’s Hospital Neonatal …
Topics in Neonatal Informatics: Infants and Data in the Electronic Health Record Era
Adoption of electronic health records continues to proceed rapidly Neonatology offers unique barriers that must be addressed within the continued development of the electronic health record Reducing these barriers can lead to improvements in the quality and safety of health-care
Topics in Neonatal Informatics: Standardizing Diagnoses in Neonatology: Bronchopulmonary Dysplasia and Beyond
There are many data efforts in neonatology established to advance improvements in quality of care for neonatal patients Challenges in the standardization and alignment of diagnoses still exist Data harmonization initiatives are underway to standardize nomenclature starting from fetal life
Neonatal Care Report
In conjunction with CHA & Alschuler Associates, CHNC serves as subject matter expert to improve the efficiency of capturing clinical data from existing electronic medical records systems to drive future neonatology QI and research initiatives View The Report